Zix MR OD 200 mg/8 mg Capsule 
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NOTICE: unsafe with : Alcohol
USED FOR:
Fever
Muscle relaxation
Headache
COMPOSITION:
Aceclofenac (200mg)
Thiocolchicoside (8mg)
Therapeutic Uses:
pain analgesics
CAUTION
Taking aceclofenac with alcohol may increase risk of stomach bleeding.
WEIGH RISKS VS BENEFITS
Zix MR OD 200 mg/8 mg Capsule may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
No information is available on the use of Zix MR OD 200 mg/8 mg Capsule during lactation. Please consult your doctor.
Zix MR OD 200 mg/8 mg Capsule may cause side effects which could affect your ability to drive.
CAUTION
Zix MR OD 200 mg/8 mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Zix MR OD 200 mg/8 mg Capsule may be needed. Please consult your doctor.Use of Zix MR OD 200 mg/8 mg Capsule is not recommended in patients with severe kidney disease.
CAUTION
Zix MR OD 200 mg/8 mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Zix MR OD 200 mg/8 mg Capsule may be needed. Please consult your doctor.Use of Zix MR OD 200 mg/8 mg Capsule is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while the patient is taking this medicine.
Uses of Aceclofenac
Aceclofenac is used in fever, headache, arthralgia, muscle pain, dental pain, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.
How to use Aceclofenac
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zix MR OD 200 mg/8 mg Capsule is to be taken with food.This will help to avoid acidity and heartburn.
How Zix MR OD 200 mg/8 mg Capsule works
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (redness and swelling), fever and pain.
Common Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Vomiting, Nausea, Indigestion.
Expert advice for Aceclofenac
It should be taken with food or milk to avoid getting an upset stomach. It can cause serious complications like stomach bleeding and kidney problems if taken for a long time. Aceclofenac can raise a risk of blood clots, heart attack, or a stroke. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Q. Is aceclofenac safe?
Aceclofenac (also available as Hifenac, Zerodol) is safe at the prescribed dose by the doctor. Patients should follow the advice of the doctor regarding its use
Q. Is aceclofenac a painkiller/ antipyretic/ antibiotic?
Aceclofenac is a pain relieving medication and not an antibiotic. It may reduce fever; however consult your doctor regarding its use
Q. Is aceclofenac better than diclofenac?
Aceclofenac is structurally related and metabolised to diclofenac. Both are equally effective and safe in relieving pain. Patients should follow the advice of the doctor regarding its use
Q. Is aceclofenac paracetamol/ aspirin?
No. Aceclofenac is not paracetamol or aspirin.
Uses of Thiocolchicoside
Thiocolchicoside is used for muscle relaxationIt relieves painful spasms of the skeletal muscles.
How to use Thiocolchicoside
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zix MR OD 200 mg/8 mg Capsule is to be taken with food.This will help to avoid acidity and heartburn.
How Zix MR OD 200 mg/8 mg Capsule works
Thiocolchicoside is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles.
Common Sleepiness, Dryness in mouth.
Expert advice for Thiocolchicoside
Thiocolchicoside can increase the effects of other CNS depressants (alcohol, barbiturates) medicine. Avoid consuming alcohol when taking the Thiocolchicoside, as it may cause excessive drowsiness and calmness. Inform your doctor if you have ever been diagnosed with kidney or liver problems. Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Q. What is Thiocolchicoside?
Thiocolchicoside is a muscle relaxant which is used in adults and adolescents from 16 years onwards as an add-on treatment for painful muscular contractions. It is to be used for acute conditions related to the spinal column.
Q. Is Thiocolchicoside a steroid?
No, Thiocolchicoside is not a steroid. It is a naturally occurring glucoside from a plant source.
Q. Thiocolchicoside is derived from which plant?
Thiocolchicoside is a semi-synthetic derivative of naturally occurring compound colchicoside from the plant Gloriosa superb.
Q. Is Thiocolchicoside safe?
Thiocolchicoside is a safe medicine if used at prescribed doses for the prescribed duration as advised by your doctor. Recently, there have been reports that one of the products formed in the body when taking Thiocolchicoside at high doses may cause damage to the some cells which could be a risk factor for cancer, harm to unborn child and impairment of male fertility. Please consult your doctor before taking this medicine.
Q. How does Thiocolchicoside works?
Thiocochicoside works by acting on the centres in the brain and spinal cord to relieve the muscle stiffness or spasm.
Q. Is Thiocolchicoside addictive?
No, Thiocolchicoside is not known to have any addiction potential.
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